S25N (p.Ser25Asn) variant of TGFB2 (P61812)
S25N (p.Ser25Asn) in TGFB2 (P61812) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
S25N (p.Ser25Asn) variant details
- p.Ser25Asn
- cosmic curated COSV65110
- Missense
- Variant Prioritization Score for Impact Estimate 0.372
- REVEL 0.10
- CADD 22.90
- PolyPhen-2 0.21
- SIFT 0.31
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available