L77V (p.Leu77Val) variant of TGFB2 (P61812)
L77V (p.Leu77Val) in TGFB2 (P61812) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
L77V (p.Leu77Val) variant details
- p.Leu77Val
- gnomAD 1-218346930-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.416
- REVEL 0.46
- CADD 24.90
- PolyPhen-2 0.73
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available