L77S (p.Leu77Ser) variant of TGFB2 (P61812)
L77S (p.Leu77Ser) in TGFB2 (P61812) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data, published literature, and structural context.
L77S (p.Leu77Ser) variant details
- p.Leu77Ser
- gnomAD 1-218346931-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.752
- REVEL 0.80
- CADD 32.00
- PolyPhen-2 0.98
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available