L27F (p.Leu27Phe) variant of TGFB2 (P61812)
L27F (p.Leu27Phe) in TGFB2 (P61812) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
L27F (p.Leu27Phe) variant details
- p.Leu27Phe
- TOPMed rs1209272897
- Missense
- Variant Prioritization Score for Impact Estimate 0.479
- REVEL 0.39
- CADD 24.00
- PolyPhen-2 0.84
- SIFT 0.10
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available