L19F (p.Leu19Phe) variant of TGFB2 (P61812)
L19F (p.Leu19Phe) in TGFB2 (P61812) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
L19F (p.Leu19Phe) variant details
- p.Leu19Phe
- TOPMed rs1305579825
- gnomAD rs1305579825
- Missense
- Variant Prioritization Score for Impact Estimate 0.382
- REVEL 0.20
- CADD 21.80
- PolyPhen-2 0.05
- SIFT 0.38
- Most common in the Non-Finnish European population (allele frequency 6.3e-06)
- Structural context available