I11F (p.Ile11Phe) variant of TGFB2 (P61812)
I11F (p.Ile11Phe) in TGFB2 (P61812) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
I11F (p.Ile11Phe) variant details
- p.Ile11Phe
- gnomAD 1-218346732-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.143
- REVEL 0.17
- CADD 7.79
- PolyPhen-2 0.00
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available