G42R (p.Gly42Arg) variant of TGFB2 (P61812)
G42R (p.Gly42Arg) in TGFB2 (P61812) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
G42R (p.Gly42Arg) variant details
- p.Gly42Arg
- cosmic curated COSV65108
- Missense
- Variant Prioritization Score for Impact Estimate 0.735
- REVEL 0.67
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available