F32Y (p.Phe32Tyr) variant of TGFB2 (P61812)
F32Y (p.Phe32Tyr) in TGFB2 (P61812) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
F32Y (p.Phe32Tyr) variant details
- p.Phe32Tyr
- gnomAD 1-218346796-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.35
- REVEL 0.15
- CADD 23.00
- PolyPhen-2 0.41
- SIFT 0.62
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available