E66A (p.Glu66Ala) variant of TGFB2 (P61812)
E66A (p.Glu66Ala) in TGFB2 (P61812) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
E66A (p.Glu66Ala) variant details
- p.Glu66Ala
- gnomAD rs1202024276
- Missense
- Variant Prioritization Score for Impact Estimate 0.394
- REVEL 0.24
- CADD 24.00
- PolyPhen-2 0.01
- SIFT 0.37
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available