D28Y (p.Asp28Tyr) variant of TGFB2 (P61812)
D28Y (p.Asp28Tyr) in TGFB2 (P61812) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data, published literature, and structural context.
D28Y (p.Asp28Tyr) variant details
- p.Asp28Tyr
- gnomAD 1-218346783-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.746
- REVEL 0.69
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available