S13C (p.Ser13Cys) variant of TG (Thyroglobulin)
S13C (p.Ser13Cys) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
S13C (p.Ser13Cys) variant details
- p.Ser13Cys
- ExAC rs753032118
- gnomAD rs753032118
- Missense
- Variant Prioritization Score for Impact Estimate 0.214
- REVEL 0.15
- MetaLR 0.21
- MetaSVM -0.89
- CADD 11.80
- PolyPhen-2 0.64
- SIFT 0.20
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available