Q25K (p.Gln25Lys) variant of TG (Thyroglobulin)
Q25K (p.Gln25Lys) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
Q25K (p.Gln25Lys) variant details
- p.Gln25Lys
- ExAC rs755777744
- TOPMed rs755777744
- gnomAD rs755777744
- Missense
- Variant Prioritization Score for Impact Estimate 0.311
- REVEL 0.18
- MetaLR 0.16
- MetaSVM -0.68
- CADD 23.10
- PolyPhen-2 0.22
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available