N65K (p.Asn65Lys) variant of TG (Thyroglobulin)
N65K (p.Asn65Lys) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
N65K (p.Asn65Lys) variant details
- p.Asn65Lys
- gnomAD 8-132869747-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.0825
- REVEL 0.04
- MetaLR 0.08
- MetaSVM -1.07
- CADD 0.00
- PolyPhen-2 0.01
- SIFT 0.91
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available