N20S (p.Asn20Ser) variant of TG (Thyroglobulin)
N20S (p.Asn20Ser) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
N20S (p.Asn20Ser) variant details
- p.Asn20Ser
- Ensembl rs1587143282
- Missense
- Variant Prioritization Score for Impact Estimate 0.337
- REVEL 0.32
- MetaLR 0.29
- MetaSVM -0.68
- CADD 21.30
- PolyPhen-2 0.78
- SIFT 0.13
- Most common in the East Asian population (allele frequency 0.00013)
- Structural context available