L3W (p.Leu3Trp) variant of TG (Thyroglobulin)
L3W (p.Leu3Trp) in TG (Thyroglobulin) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
L3W (p.Leu3Trp) variant details
- p.Leu3Trp
- gnomAD 8-132867004-GC-G
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.444
- CADD 22.80
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available