L3P (p.Leu3Pro) variant of TG (Thyroglobulin)
L3P (p.Leu3Pro) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
L3P (p.Leu3Pro) variant details
- p.Leu3Pro
- ExAC rs755500716
- gnomAD rs755500716
- Missense
- Variant Prioritization Score for Impact Estimate 0.275
- REVEL 0.28
- MetaLR 0.19
- MetaSVM -0.85
- CADD 20.20
- PolyPhen-2 0.01
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available