L31P (p.Leu31Pro) variant of TG (Thyroglobulin)
L31P (p.Leu31Pro) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
L31P (p.Leu31Pro) variant details
- p.Leu31Pro
- gnomAD rs1404590444
- Missense
- Variant Prioritization Score for Impact Estimate 0.523
- REVEL 0.47
- MetaLR 0.44
- MetaSVM -0.04
- CADD 27.40
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available