L31F (p.Leu31Phe) variant of TG (Thyroglobulin)
L31F (p.Leu31Phe) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
L31F (p.Leu31Phe) variant details
- p.Leu31Phe
- gnomAD 8-132868138-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.471
- REVEL 0.39
- MetaLR 0.49
- MetaSVM -0.38
- CADD 24.30
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available
- Literature evidence available