L11Q (p.Leu11Gln) variant of TG (Thyroglobulin)
L11Q (p.Leu11Gln) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
L11Q (p.Leu11Gln) variant details
- p.Leu11Gln
- gnomAD 8-132867032-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.425
- REVEL 0.38
- MetaLR 0.34
- MetaSVM -0.61
- CADD 24.00
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available