L11P (p.Leu11Pro) variant of TG (Thyroglobulin)
L11P (p.Leu11Pro) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
L11P (p.Leu11Pro) variant details
- p.Leu11Pro
- gnomAD rs1278421972
- Missense
- Variant Prioritization Score for Impact Estimate 0.467
- REVEL 0.46
- MetaLR 0.33
- MetaSVM -0.49
- CADD 24.20
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the East Asian population (allele frequency 5.1e-05)
- Structural context available