L11M (p.Leu11Met) variant of TG (Thyroglobulin)
L11M (p.Leu11Met) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
L11M (p.Leu11Met) variant details
- p.Leu11Met
- gnomAD 8-132867031-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.245
- REVEL 0.13
- MetaLR 0.30
- MetaSVM -0.78
- CADD 21.90
- PolyPhen-2 0.96
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available