L10V (p.Leu10Val) variant of TG (Thyroglobulin)
L10V (p.Leu10Val) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
L10V (p.Leu10Val) variant details
- p.Leu10Val
- gnomAD 8-132867028-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.345
- REVEL 0.27
- MetaLR 0.31
- MetaSVM -0.78
- CADD 19.80
- PolyPhen-2 0.99
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available