I21V (p.Ile21Val) variant of TG (Thyroglobulin)
I21V (p.Ile21Val) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
I21V (p.Ile21Val) variant details
- p.Ile21Val
- 1000Genomes rs574422251
- TOPMed rs574422251
- gnomAD rs574422251
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.06
- MetaLR 0.12
- MetaSVM -0.98
- CADD 16.30
- PolyPhen-2 0.10
- SIFT 0.12
- Most common in the 1KG:CDX population (allele frequency 0.0057)
- Structural context available