I14T (p.Ile14Thr) variant of TG (Thyroglobulin)
I14T (p.Ile14Thr) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
I14T (p.Ile14Thr) variant details
- p.Ile14Thr
- ExAC rs577354103
- gnomAD rs577354103
- Missense
- Variant Prioritization Score for Impact Estimate 0.181
- REVEL 0.07
- MetaLR 0.15
- MetaSVM -0.95
- CADD 3.36
- PolyPhen-2 0.00
- SIFT 0.51
- Most common in the South Asian population (allele frequency 2.4e-05)
- Structural context available