I14S (p.Ile14Ser) variant of TG (Thyroglobulin)
I14S (p.Ile14Ser) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
I14S (p.Ile14Ser) variant details
- p.Ile14Ser
- ExAC rs577354103
- gnomAD rs577354103
- Missense
- Variant Prioritization Score for Impact Estimate 0.186
- REVEL 0.07
- MetaLR 0.15
- MetaSVM -0.94
- CADD 6.41
- PolyPhen-2 0.00
- SIFT 0.39
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available