I14L (p.Ile14Leu) variant of TG (Thyroglobulin)
I14L (p.Ile14Leu) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
I14L (p.Ile14Leu) variant details
- p.Ile14Leu
- 1000Genomes rs544043844
- TOPMed rs544043844
- gnomAD rs544043844
- Missense
- Variant Prioritization Score for Impact Estimate 0.104
- REVEL 0.04
- MetaLR 0.12
- MetaSVM -1.07
- CADD 0.03
- PolyPhen-2 0.00
- SIFT 0.79
- Most common in the 1KG:MSL population (allele frequency 0.0063)
- Structural context available