F58L (p.Phe58Leu) variant of TG (Thyroglobulin)
F58L (p.Phe58Leu) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
F58L (p.Phe58Leu) variant details
- p.Phe58Leu
- ExAC rs748159184
- TOPMed rs748159184
- gnomAD rs748159184
- Missense
- Variant Prioritization Score for Impact Estimate 0.64
- REVEL 0.71
- MetaLR 0.57
- MetaSVM 0.41
- CADD 26.40
- PolyPhen-2 0.77
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available