F22I (p.Phe22Ile) variant of TG (Thyroglobulin)
F22I (p.Phe22Ile) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
F22I (p.Phe22Ile) variant details
- p.Phe22Ile
- gnomAD 8-132867064-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.348
- REVEL 0.31
- MetaLR 0.16
- MetaSVM -0.74
- CADD 22.30
- PolyPhen-2 0.13
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available