D66E (p.Asp66Glu) variant of TG (Thyroglobulin)
D66E (p.Asp66Glu) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
D66E (p.Asp66Glu) variant details
- p.Asp66Glu
- gnomAD 8-132869750-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.144
- REVEL 0.17
- MetaLR 0.10
- MetaSVM -0.99
- CADD 0.00
- PolyPhen-2 0.38
- SIFT 0.24
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available