C63F (p.Cys63Phe) variant of TG (Thyroglobulin)
C63F (p.Cys63Phe) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.87 / 1. The record also includes population frequency data, published literature, and structural context.
C63F (p.Cys63Phe) variant details
- p.Cys63Phe
- gnomAD 8-132869740-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.865
- REVEL 0.91
- MetaLR 0.86
- MetaSVM 0.96
- CADD 26.20
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available
- Literature evidence available