C15Y (p.Cys15Tyr) variant of TG (Thyroglobulin)
C15Y (p.Cys15Tyr) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
C15Y (p.Cys15Tyr) variant details
- p.Cys15Tyr
- TOPMed rs1268394257
- gnomAD rs1268394257
- Missense
- Variant Prioritization Score for Impact Estimate 0.32
- REVEL 0.29
- MetaLR 0.18
- MetaSVM -0.88
- CADD 15.50
- PolyPhen-2 0.56
- SIFT 0.13
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available