C15S (p.Cys15Ser) variant of TG (Thyroglobulin)
C15S (p.Cys15Ser) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
C15S (p.Cys15Ser) variant details
- p.Cys15Ser
- TOPMed rs1268394257
- gnomAD rs1268394257
- Missense
- Variant Prioritization Score for Impact Estimate 0.212
- REVEL 0.13
- MetaLR 0.12
- MetaSVM -0.99
- CADD 6.73
- PolyPhen-2 0.01
- SIFT 0.42
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available