C15F (p.Cys15Phe) variant of TG (Thyroglobulin)
C15F (p.Cys15Phe) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
C15F (p.Cys15Phe) variant details
- p.Cys15Phe
- TOPMed rs1268394257
- gnomAD rs1268394257
- Missense
- Variant Prioritization Score for Impact Estimate 0.307
- REVEL 0.25
- MetaLR 0.15
- MetaSVM -0.91
- CADD 19.10
- PolyPhen-2 0.47
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 7.2e-06)
- Structural context available