A53S (p.Ala53Ser) variant of TG (Thyroglobulin)
A53S (p.Ala53Ser) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
A53S (p.Ala53Ser) variant details
- p.Ala53Ser
- TOPMed rs1324784516
- gnomAD rs1324784516
- Missense
- Variant Prioritization Score for Impact Estimate 0.0789
- REVEL 0.03
- MetaLR 0.07
- MetaSVM -1.03
- CADD 0.30
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available