A2S (p.Ala2Ser) variant of TG (Thyroglobulin)
A2S (p.Ala2Ser) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
A2S (p.Ala2Ser) variant details
- p.Ala2Ser
- gnomAD 8-132867004-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.208
- REVEL 0.04
- MetaLR 0.15
- MetaSVM -0.93
- CADD 22.10
- PolyPhen-2 0.14
- SIFT 0.22
- Population evidence available
- Structural context available
- Literature evidence available