A2G (p.Ala2Gly) variant of TG (Thyroglobulin)
A2G (p.Ala2Gly) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
A2G (p.Ala2Gly) variant details
- p.Ala2Gly
- gnomAD 8-132867005-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.157
- REVEL 0.03
- MetaLR 0.14
- MetaSVM -0.97
- CADD 15.90
- PolyPhen-2 0.01
- SIFT 0.23
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available