A2D (p.Ala2Asp) variant of TG (Thyroglobulin)
A2D (p.Ala2Asp) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
A2D (p.Ala2Asp) variant details
- p.Ala2Asp
- gnomAD 8-132867005-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.252
- REVEL 0.18
- MetaLR 0.18
- MetaSVM -0.91
- CADD 20.40
- PolyPhen-2 0.42
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available