A12S (p.Ala12Ser) variant of TG (Thyroglobulin)
A12S (p.Ala12Ser) in TG (Thyroglobulin) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
A12S (p.Ala12Ser) variant details
- p.Ala12Ser
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.165
- REVEL 0.06
- MetaLR 0.07
- MetaSVM -0.96
- CADD 8.49
- PolyPhen-2 0.00
- SIFT 0.92
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available