A12D (p.Ala12Asp) variant of TG (Thyroglobulin)
A12D (p.Ala12Asp) in TG (Thyroglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
A12D (p.Ala12Asp) variant details
- p.Ala12Asp
- gnomAD 8-132867035-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.13
- MetaLR 0.10
- MetaSVM -1.03
- CADD 4.17
- PolyPhen-2 0.00
- SIFT 0.64
- Population evidence available
- Structural context available
- Literature evidence available