T52I (p.Thr52Ile) variant of TET2 (Methylcytosine dioxygenase TET2)
T52I (p.Thr52Ile) in TET2 (Methylcytosine dioxygenase TET2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
T52I (p.Thr52Ile) variant details
- p.Thr52Ile
- gnomAD 4-105234097-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.266
- REVEL 0.04
- MetaLR 0.04
- MetaSVM -1.05
- CADD 6.10
- PolyPhen-2 0.00
- SIFT 0.42
- Population evidence available
- Structural context available
- Literature evidence available