T32A (p.Thr32Ala) variant of TET2 (Methylcytosine dioxygenase TET2)
T32A (p.Thr32Ala) in TET2 (Methylcytosine dioxygenase TET2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
T32A (p.Thr32Ala) variant details
- p.Thr32Ala
- gnomAD 4-105234036-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0848
- REVEL 0.06
- MetaLR 0.03
- MetaSVM -1.03
- CADD 1.16
- PolyPhen-2 0.00
- SIFT 0.14
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available
- Literature evidence available