S38G (p.Ser38Gly) variant of TET2 (Methylcytosine dioxygenase TET2)
S38G (p.Ser38Gly) in TET2 (Methylcytosine dioxygenase TET2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
S38G (p.Ser38Gly) variant details
- p.Ser38Gly
- ExAC rs763846739
- gnomAD rs763846739
- Missense
- Variant Prioritization Score for Impact Estimate 0.181
- REVEL 0.06
- MetaLR 0.08
- MetaSVM -1.00
- CADD 22.90
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available