S15R (p.Ser15Arg) variant of TET2 (Methylcytosine dioxygenase TET2)
S15R (p.Ser15Arg) in TET2 (Methylcytosine dioxygenase TET2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
S15R (p.Ser15Arg) variant details
- p.Ser15Arg
- gnomAD 4-105233915-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.593
- CADD 18.10
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available