S15N (p.Ser15Asn) variant of TET2 (Methylcytosine dioxygenase TET2)
S15N (p.Ser15Asn) in TET2 (Methylcytosine dioxygenase TET2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
S15N (p.Ser15Asn) variant details
- p.Ser15Asn
- gnomAD rs1436240000
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.19
- MetaLR 0.21
- MetaSVM -0.66
- CADD 23.60
- PolyPhen-2 1.00
- SIFT 0.12
- Most common in the Latino/Admixed American population (allele frequency 6.7e-05)
- Structural context available