R13G (p.Arg13Gly) variant of TET2 (Methylcytosine dioxygenase TET2)
R13G (p.Arg13Gly) in TET2 (Methylcytosine dioxygenase TET2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
R13G (p.Arg13Gly) variant details
- p.Arg13Gly
- gnomAD 4-105233979-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- REVEL 0.15
- MetaLR 0.08
- MetaSVM -0.99
- CADD 21.70
- PolyPhen-2 0.01
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available