Q35H (p.Gln35His) variant of TET2 (Methylcytosine dioxygenase TET2)
Q35H (p.Gln35His) in TET2 (Methylcytosine dioxygenase TET2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
Q35H (p.Gln35His) variant details
- p.Gln35His
- gnomAD 4-105234047-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.246
- REVEL 0.11
- MetaLR 0.17
- MetaSVM -0.75
- CADD 24.20
- PolyPhen-2 1.00
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available