Q35* (p.Gln35Ter) variant of TET2 (Methylcytosine dioxygenase TET2)
Q35* (p.Gln35Ter) in TET2 (Methylcytosine dioxygenase TET2) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.86 / 1. The record also includes population frequency data and structural context.
Q35* (p.Gln35Ter) variant details
- p.Gln35Ter
- cosmic curated COSV54436
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.86
- CADD 36.00
- Most common in the Ashkenazi Jewish population (allele frequency 3.8e-05)
- Structural context available