Q26R (p.Gln26Arg) variant of TET2 (Methylcytosine dioxygenase TET2)
Q26R (p.Gln26Arg) in TET2 (Methylcytosine dioxygenase TET2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
Q26R (p.Gln26Arg) variant details
- p.Gln26Arg
- cosmic curated COSV10502
- Missense
- Variant Prioritization Score for Impact Estimate 0.227
- REVEL 0.11
- MetaLR 0.14
- MetaSVM -0.71
- CADD 23.50
- PolyPhen-2 0.82
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available