H55Y (p.His55Tyr) variant of TET2 (Methylcytosine dioxygenase TET2)
H55Y (p.His55Tyr) in TET2 (Methylcytosine dioxygenase TET2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
H55Y (p.His55Tyr) variant details
- p.His55Tyr
- gnomAD rs1291107913
- Missense
- Variant Prioritization Score for Impact Estimate 0.233
- REVEL 0.06
- MetaLR 0.04
- MetaSVM -1.05
- CADD 12.40
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available