H45P (p.His45Pro) variant of TET2 (Methylcytosine dioxygenase TET2)
H45P (p.His45Pro) in TET2 (Methylcytosine dioxygenase TET2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
H45P (p.His45Pro) variant details
- p.His45Pro
- gnomAD 4-105234076-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.107
- REVEL 0.06
- MetaLR 0.04
- MetaSVM -1.03
- CADD 7.81
- PolyPhen-2 0.00
- SIFT 0.17
- Population evidence available
- Structural context available
- Literature evidence available